×
Entrez Id: 80781
Gene Symbol: COL18A1
COL18A1
Malignant neoplasm of liver
0.240
ModifyingMutation
RGD
Combined endostatin/sFlt-1 antiangiogenic gene therapy is highly effective in a rat model of HCC.
15739185 2005
×
Entrez Id: 407014
Gene Symbol: MIR25
MIR25
Malignant neoplasm of liver
0.230
ModifyingMutation
RGD
Upregulation of microRNA-25 associates with prognosis in hepatocellular carcinoma.
24593846 2014
×
Entrez Id: 407014
Gene Symbol: MIR25
MIR25
Malignant neoplasm of liver
0.230
ModifyingMutation
RGD
A novel SOCS5/miR-18/miR-25 axis promotes tumorigenesis in liver cancer .
30191950 2019
×
Entrez Id: 406937
Gene Symbol: MIR145
MIR145
Malignant neoplasm of liver
0.230
ModifyingMutation
RGD
Investigation of the clinical significance and prognostic value of microRNA-145 in human hepatocellular carcinoma.
30572504 2018
×
Entrez Id: 407050
Gene Symbol: MIR93
MIR93
Malignant neoplasm of liver
0.210
ModifyingMutation
RGD
The miR-93 promotes proliferation by directly targeting PDCD4 in hepatocellular carcinoma.
28592130 2019
×
Entrez Id: 406900
Gene Symbol: MIR106B
MIR106B
Malignant neoplasm of liver
0.200
ModifyingMutation
RGD
Study on the value of serum miR-106b for the early diagnosis of hepatocellular carcinoma.
28611524 2017
×
Entrez Id: 407053
Gene Symbol: MIR96
MIR96
Malignant neoplasm of liver
0.200
ModifyingMutation
RGD
Wnt/β-Catenin activates MiR-183/96/182 expression in hepatocellular carcinoma that promotes cell invasion.
25813403 2015
×
Entrez Id: 406953
Gene Symbol: MIR18A
MIR18A
Malignant neoplasm of liver
0.200
ModifyingMutation
RGD
A novel SOCS5/miR-18 /miR-25 axis promotes tumorigenesis in liver cancer .
30191950 2019
×
Entrez Id: 406953
Gene Symbol: MIR18A
MIR18A
Malignant neoplasm of liver
0.200
ModifyingMutation
RGD
MicroRNA-18a promotes hepatocellular carcinoma proliferation, migration, and invasion by targeting Bcl2L10.
30519035 2018
×
Entrez Id: 406971
Gene Symbol: MIR195
MIR195
Malignant neoplasm of liver
0.200
ModifyingMutation
RGD
MicroRNA-195 functions as a tumor suppressor by inhibiting CBX4 in hepatocellular carcinoma.
25607636 2015
×
Entrez Id: 406900
Gene Symbol: MIR106B
MIR106B
Malignant neoplasm of liver
0.200
ModifyingMutation
RGD
MicroRNA-106b-5p promotes hepatocellular carcinoma development via modulating FOG2.
31406464 2019
×
Entrez Id: 55607
Gene Symbol: PPP1R9A
PPP1R9A
Malignant neoplasm of liver
0.200
ModifyingMutation
RGD
Mitochondrial prohibitins and septin 9 are implicated in the onset of rat hepatocarcinogenesis.
20935162 2011
×
Entrez Id: 5465
Gene Symbol: PPARA
PPARA
Malignant neoplasm of liver
0.550
SusceptibilityMutation
RGD
PPAR-alpha L162V polymorphism in human hepatocellular carcinoma.
19119483 2008
×
Entrez Id: 5428
Gene Symbol: POLG
POLG
Malignant neoplasm of liver
0.200
SusceptibilityMutation
RGD
Polymorphisms in POLG were associated with the prognosis and mtDNA content in hepatocellular carcinoma patients.
28457473 2017
×
Entrez Id: 4176
Gene Symbol: MCM7
MCM7
Malignant neoplasm of liver
0.200
SusceptibilityMutation
RGD
A genetic variant in the promoter region of miR-106b-25 cluster predict clinical outcome of HBV-related hepatocellular carcinoma in Chinese.
24416400 2014
×
Entrez Id: 7157
Gene Symbol: TP53
TP53
Malignant neoplasm of liver
0.600
AlteredExpression
BEFREE
These results indicate that p53 is overexpressed in a majority of childhood liver cancers , but this abnormal p53 expression does not seem to be caused by mutations in the p53 gene.
8200636 1994
×
Entrez Id: 7157
Gene Symbol: TP53
TP53
Malignant neoplasm of liver
0.600
AlteredExpression
BEFREE
Correlation between expression levels of PTEN and p53 genes and the clinical features of HBsAg-positive liver cancer .
28952211 2019
×
Entrez Id: 7157
Gene Symbol: TP53
TP53
Malignant neoplasm of liver
0.600
AlteredExpression
BEFREE
LncRNA SNHG1 promotes liver cancer development through inhibiting p53 expression via binding to DNMT1.
31002127 2019
×
Entrez Id: 7157
Gene Symbol: TP53
TP53
Malignant neoplasm of liver
0.600
AlteredExpression
BEFREE
A mouse model of liver cancer reveals that downregulation of mevalonate pathway gene expression by p53 occurs in premalignant hepatocytes, when p53 is needed to actively suppress tumorigenesis.
30580964 2019
×
Entrez Id: 7157
Gene Symbol: TP53
TP53
Malignant neoplasm of liver
0.600
AlteredExpression
BEFREE
Thus, detection of the codon 249 mutant p53 mRNA by differential in situ hybridization is a specific method for studying the mutation-specific expression of the p53 gene in liver cancers at the cellular level, while simultaneously visualizing the cell morphology.
7567152 1995
×
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
Malignant neoplasm of liver
0.590
AlteredExpression
BEFREE
Role of HSP90, CDC37, and CRM1 as modulators of P16(INK4A ) activity in rat liver carcinogenesis and human liver cancer .
16317707 2005
×
Entrez Id: 4609
Gene Symbol: MYC
MYC
Malignant neoplasm of liver
0.590
AlteredExpression
BEFREE
Considering the possibility that MYC may amplify the expression of PPARA target genes to potentiate cell proliferation and liver cancer , gene expression was analyzed from livers of wild-type and liver-specific Myc knockout (Myc<sup>ΔHep</sup> ) mice treated with the PPARA agonist pirinixic acid.
30697791 2019
×
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
Malignant neoplasm of liver
0.590
AlteredExpression
BEFREE
The p16 protein expressions in liver cancer and para-carcinoma tissues were detected via immunohistochemistry (IHC), and the correlations of p16 positive expression with ultrasound parameters were also analyzed.
30509095 2019
×
Entrez Id: 27232
Gene Symbol: GNMT
GNMT
Malignant neoplasm of liver
0.560
AlteredExpression
BEFREE
Reduced GNMT expression was also found in human HCC tissue and liver cancer cell lines.
31086990 2019
×
Entrez Id: 27232
Gene Symbol: GNMT
GNMT
Malignant neoplasm of liver
0.560
AlteredExpression
BEFREE
Down-regulation of GNMT gene expression may be involved in the pathogenesis of liver cancer .
9495250 1998